Accomodating intraocular

The iterative mathematical modeling based upon the prototype yielded maximized optical and mechanical performance through maximum allowable gel thickness to extrusion diameter ratio, maximum feasible refractive index change at the interface, and minimum gel material properties in Poisson's ratio and Young's modulus. It operated within the physiologic constraints of the human eye including the force available for full accommodative amplitude using the eye's natural focusing feedback, while maintaining image quality in the space available.

The parameters that optimized optical and mechanical performance were delineated as those, which minimize both asphericity and actuation pressure.

The next generation design of extruded gel interface intraocular lens is presented.

A prototype based upon similar previously in vivo proven design was tested with measurements of actuation force, lens power, interface contour, optical transfer function, and visual Strehl ratio.

For activities such as computer work or reading, they need separate glasses.

The increasing spherical deformation creates a variable lens that is directly proportional to the force applied to it by the zonular tension.

Mechanically accommodating lenses rely upon the complex autonomic negative feedback control present in natural accommodation, which adjust the zonular tension to maximize the image clarity of a visual target.

The glycerin had a higher refractive index at 1.47 than the silicone gel at 1.43, thereby creating an increasingly negative powered lens as the silicone gel is extruded.

The modulus of elasticity of the silicone gel was approximately 1.0 KPa with a Poisson's ratio of 0.49.

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